Effect of Xanthorrhizol on Streptococcus mutans Bioflims In Vitro  

Oleh:

Rukayadi, Yaya ; Hwang, Jae-Kwan

Jenis: Article from Journal - ilmiah nasional
Dalam koleksi: Jurnal Mikrobiologi Indonesia vol. 11 no. 1 (Feb. 2006), page 40.
Topik: xanthorrhizol; Streptococcus mutans; antibacterial biofiim

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: JJ139 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Bioproducts Research Center, Yonsei University, 134 Sinchon-dong, Seodaemun-gu, Seoul 120-749, Korea Streptococcus mutans is one of the first colonizers of dental surface, where, together with many other bacterial species, they build a biofilm also known as dental plaque. The aim of this study was to determine the effect of xanthorrhizol isolated from the rhizome of java turmeric (Curcuma xanthorrhiza) on the S. mulans biofilms in vitro. The biofilms of S. muans at different phases of growth were exposed to xanthorrhizol at different concentration (5, 10, and 50 jiM) and for different exposure time (1, 10, and 30 mm). The results demonstrated that 5 jiM of xanthorrhizol completely removed biofilm formation by S. mutans at adherent phases of growth, and 50 jiM of xanthorrhizol removed 61% of biofilm at slow or plateau accumulated phase when exposed to S. mutans biofilm for 30 mm. These results indicated that xanthorrhizol could be used as a potential antibacterial agent against S. mutans biofilms.

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