Produksi Asam Hialuronat oleh Streptococcus Zooepidemicus ATCC 39920  

Oleh:

Martius, Efrida ; Sa'id, Endang Gumbira ; Noor, Erliza ; Fahma, Fakrida

Jenis: Article from Journal - ilmiah nasional
Dalam koleksi: Jurnal Mikrobiologi Indonesia vol. 11 no. 1 (Feb. 2006), page 5.
Topik: mikrobiologi; cholesterol; stability; Lactobacillus sp; .probiotic; dried cell

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: JJ139 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Hyaluronic Acid (HA) produced for pharmaceuticals, medical, and cosmetic industries is a high molecular weight of linear polysaceharide. HA, the cementing substance in connective tissue can be extracted from rooster comb and umbilical cord. More recently, the HA production has been enhanced by microbial cultivation. The objective of this research was to optimize the HA production by using media containing different concentrations of Na 2HPO4~2H2O; KH2P01'7H20; MgSO4~7H2Oand amino acids. The effects of temperature (33, 37, and 40 'C) and agitation were also observed in batch cultures. Result show that medium containing high concentration of Na2HPO;2H20 and complete amino acids gave high viscosity. The HA production was relatively better in the agitated culture than that in without agitation. The highest production of 9.7 g I' was observed in the culture at 100 rpm and 37 'C.

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