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ArtikelPeran Glukosamin sebagai Kondroprotektor  
Oleh: Susanto, Budi
Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI - atma jaya
Dalam koleksi: Majalah Kedokteran Damianus vol. 04 no. 02 (May 2005), page 119-127.
Topik: ARTHRITIS; Glucosamine; Osteoarthritis; Chondroprotector
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    • Nomor Panggil: D01.K.2006.K
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Isi artikelOsteoarthritis is a disease showing change of structure and function of the joints caused by progressive degeneration and destruction of the joint cartilage. this disease can be treated by orally administration of glucosamine sulfate. glucosamine is an amino sugar that is physiologically used both as substrate and precursor for the biosynthesis of glycosaminoglycan and proteoglycan. proteoglycan, collagen type II together with water constitute the predominant components of the cartilage matrix. in a normal joint, the chondrocytes are able to produce sufficient glucosamine, whereas in osteoarthritis the biosynthesis of glucosamine is defective and insufficient, resulting in an insufficient production of glycosaminoglycan and proteoglycan.
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