Sintesis Dibenzoil Resorsinol dari Benzoil Klorida dan Resorsinol melalui Modifikasi Metode Schotten-Baumann  

Oleh:

Joyce ; Pudjono ; Cen Jung

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: SIGMA: Jurnal Sains dan teknologi vol. 5 no. 1 (Jan. 2002), page 59-66.
Topik: modification of schotten-baumann method; resorcinol; dibenzoyl resorcinol; benzoyl chloride

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: SS25.3 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Since dibenzoyl resorcinol is a kind of ester compound, it was supposed that enzyme in microorganism consuming it would hydrolize dibenzoyl resorcinol, yielding one molecul of resorcinol and two molecul of benzoic acids. Both of these compounds have antimicrobe properties, and so it is expected that they would increase the antiseptic activity of resorcinol. In this research dibenzoyl resorcinol was synthesized by reacting resorcinol and benzoyl chloride in pyridine as a solvent (modification of Schotten-Baumann method). The result analysis shows that synthetic product is a polish white powder, odorless, and tasteless. It does not contain hydroxy aromatic group such as resorcinol as a starting material, since it reacts negatively with FeCl3. It is insoluble in water but soluble in many organic solvents like eter, benzene, and chloroform. Melting point of synthetic product (117C) is higher than resorcinol (109C). Thin Layer Chromatography (TLC) test shows that the spot of synthetic product has Rf value of 0.93, which is different fro the Rf value of resorcinol (0.53). Structure elucidation of the synthetic product by Infrared (IR) and Nuclear Magnetic Resonance (NMR) spectroscopy shows spectra features, which are identified as the structure of dibenzoyl resorcinol. Mass Spectroscopy (MS) spectrum has molecul ionic peak which is in accordance with molecul weight of dibenzoyl resorcinol (318). Based on the above analysis, it is concluded that the synthetic product is indeed dibenzoyl resorcinol with a rendement of 51,54%.

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