Pemeriksaan Efek Samping Celecobix Dibandingkan Dengan Natrium Diklofenak Pada Saluran Cerna Tikus (Rattus Norvergicus) Galur Wistar  

Oleh:

Revilla, Gusti ; Katar, yusticia ; Masdar, Huriatul

Jenis: Article from Journal - ilmiah nasional
Dalam koleksi: Andalas: Jurnal Penelitian vol. 14 no. 37 (Jan. 2002), page 47-60.

Ketersediaan

Perpustakaan PKPM Nomor Panggil: A67 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Almost an NSAIDs preparations can result in the development officer within the alimentary canal. This is due to blockage of a constitutive isozyme, cyclooxygenase-l (COX-l), while the production of Prostaglandin (PG) in irtj1amed tissue is caused by an inducible isozyme, COX-2. Based un this principle, the blockage of COX-2 will exert the anti-inflammation effect without impinging on. The alimentary tract. Therefore, NSAIDs that selectively blocks COX-2 can be seen as relatively non-toxic.

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