Nature X Nurture : Genetic Vulnerabilities Interact With Physical Maltreatment to Promote Conduct Problems  

Oleh:

Rutter, Michael ; Dodge, Kenneth A. ; Caspi, Avshalom ; Tully, Lucy A. ; Jaffee, Sara R. ; Moffitt, Terrie E. ; Taylor, Alan

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Development and Psychopathology vol. 17 no. 1 (2005), page 67-84.
Topik: child maltreatment; physical maltreatment; promote conduct problems; genetic vulnerabilities interact; nature; nurture
Fulltext: DD21_17_01_SARA R. JAFFEE.pdf (206.96KB)

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Perpustakaan Pusat (Semanggi) Nomor Panggil: DD21.8 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Maltreatment places children at risk for psychiatric morbidity, especially conduct problems. However, not all maltreated children develop conduct problems. We tested whether the effect of physical maltreatment on risk for conduct problems was strongest among those who were at high genetic risk for these problems using data from the E - risk study, a reperesentative cohort of 1,116 5 - year - old british twin pairs and their families. Children's conduct problems were ascertained via parent and teacher interviews. Physical maltreatment was ascertained via parent report. Children's genetic risk for conduct problems was estimated as a function of their co - twin;s conduct disorder status and the pair's zygosity. The effect of maltreatment on risk for conduct problems was strongest among those at high genetic risk. The experience of maltreatment was associated with an increase of 2 % in th eprobability of a conduct disorder diagnosis among children at low genetic risk for conduct disorder but an increase of 24 % among children at high genetic risk. Prerdiction of behavioural pathology cna attaine greater accuracy if both pathogenic environments and genetic risk are ascertained. Certain genotypes may promote resistnace to trauma. Physically maltreated children whose first - degree relatives engage in antisocial behaviour warrant priority for therapeutic intervention.

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