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Multifocal Motor Neuropathy Associated With Infliximab: A Case Report and a Literature Review
Oleh:
Bayrak, Ayse O.
;
Ulusoy, Hasan
;
Bolat, Necdet
;
Dogan, Baki
;
Ozbenli, Taner
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
The Neurologist vol. 22 no. 04 (Jul. 2017)
,
page 144-146.
Topik:
Multifocal Motor Neuropathy
;
Infliximab
;
Tumor Necrosis Factor-a Blocker
Fulltext:
N06 v22 n4 p146 kelik2017.pdf
(66.06KB)
Ketersediaan
Perpustakaan FK
Nomor Panggil:
N06.K
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Multifocal motor neuropathy with conduction block (MMN-CB) is purely a motor neuropathy with progressive weakness that is characteristically caused by conduction blocks. Association with antiganglioside antibodies and a good response to immunomodulating therapies suggest an autoimmune etiology. In rare cases, MMN-CB has been reported as an adverse effect of infliximab, a tumor necrosis factor-a blocker. We present a case of MMN-CB due to infliximab in a 45-year-old man with psoriatic arthritis who was exposed to the drug for 2 years because of a delayed diagnosis. We emphasize the possibility of this adverse effect and the importance of detailed electrophysiological examinations, which is supported by a review of the literature.
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