Molecular Aspect Correlation Between Glycated Hemoglobin (HBA1C), Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) on Type 2 Diabetes Mellitus (T2DM)  

Oleh:

Indranila K. S.

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Indonesian Journal of Clinical Pathology and Medical Laboratory vol. 23 no. 01 (Nov. 2016), page 1-6.
Topik: Molecular Aspect; HbA1c; PT; APTT; DMT2
Fulltext: I01 v23 n1 p1 kelik2017.pdf (345.08KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: I01.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Diabetes mellitus (DM) requires glycemic control which can be determined by performing a glycated hemoglobin (HbA1c). The higher levels of glycated hemoglobin (HbA1c), the more uncontrolled blood sugar levels of patients with type 2 diabetes This can lead to a hypercoagulable process, microvascular and macrovascular disorders. Examination Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) is expected to detect at an early stage coagulation disorders in patients with diabetes mellitus type 2. The cross-sectional study of 72 people with type 2 diabetes patients aged over 18 years, to be assessed HbA1c levels and biomarkeragulation ( PT and APTT). Patients with concomitant diseases such as anemia and hemoglobin disorders, malignancy or haematological disorders, post-surgical, hyperthyroidism, pregnant women, history of liver disease and patients taking drugs that interfere with coagulation function were excluded from this study. Test data normality using the Kolmogorov-Smirnov test and analysis correlation using the Pearson test. Correlation analysis of the relationship between glycated hemoglobin levels with the Prothrombin Time shows a weak negative (r = -0.179; p = 0.132), and with Activated Partial Thromboplastin Time a very weak positive (r = 0.016; p = 0.892). Based on this results the conclusion were a weak negative correlation significantly between glycated hemoglobin levels with PT and very weak positive correlation insignificant with Activated Partial Thomboplastin Time.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali