DPPH Radical Scavenging Activity of Aqueous Fraction from Ethanolic Extract of Talok Fruit (Muntingia calabura L.)  

Oleh:

Irianti, Tatang ; Murti, Yosi Bayu ; Kanistri, Damiana Nitya ; Pratiwi, Desi Riza ; Kuswandi ; Kusumaningtyas, Ratih Anggar

Jenis: Article from Journal - ilmiah internasional - tidak terdaftar di DIKTI
Dalam koleksi: Majalah Obat Tradisional vol. 21 no. 01 (Jan. 2016), page 38-47.
Topik: Talok Fruits (Muntingia calabura L.); Antioxidant; DPPH; Acid Hydrolysis; Alkaline Hydrolysis
Fulltext: M01 v21 n1 p38 kelik2017.pdf (990.94KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: M01.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The investigation of talok fruits (Muntingia calabura L.) was shown the antioxidant activity of aqueous fraction of the ethanolic extract is relatively low. Hydrolysis treatment has increased the antioxidant activity by releasing the flavonoid aglycone from glycoside form. This study aims to determine the effect of acid and alkaline hydrolysis, and hydrolysis time on the antioxidant activity of aqueous fraction of calabura fruits ethanolic extract. The antioxidant activity of acid hydrolyzed aqueous fractions in 1 and 3h hydrolysis, respectively 9.5 and 1.5 times more potent than the aqueous fraction, while the alkaline in 1 and 3h hydro- lysis were 2.5 and 6.5 times. Flavonoid aglycone liberated on acid hydrolysis and alkaline had different anti - oxidant activity. The value of IC50 by acid hydrolyzed aqueous fraction in 1h and 3h hydrolysis of 20.55 and 97.88µg/mL, while the alkaline in 1h and 3h hydrolysis of 66.64 and 25.53µg/mL. One hour acid hydrolysis had antioxidant activity greater than 3h whereas in alkaline the greatest antioxidant activity is shown in 3h.

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