Antioxidant, Antibacterial Potential and HPLC Analysis of Dioscorea Alata Bulb  

Oleh:

Anisuzzman ; Zilani, Nazmul Hasan ; Khushi, Sharmin Sultana ; Asaduzzman ; Hossain, Golam

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Indonesian Journal of Pharmacy vol. 27 no. 01 (Jan. 2016), page 9-14.
Topik: Total Phenolic Content; Myricetin; Scavenging Activity; Disc Diffusion
Fulltext: I03 v27 n1 p9 kelik2017.pdf (638.24KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: I03.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The purpose of the present study was to evaluate antioxidant, antibacterial potential and HPLC analysis of methanol extract of Dioscorea alata bulb. Antioxidant activity investigated by DPPH free radical scavenging assay, the IC50 value of plant extract was 24.99µg/mL. Significant absorption of extract (1.317 of 1mg/mL) showed the ferric reducing activity. HPLC analysis indicated the presence of myricetin (471.53mg/100 g of dry extract) in the highest concentration. Extract showed significant zone of inhibition in antibacterial activity test. The presence of myricetin along with other detected polyphenols might contribute to antioxidant and antibacterial activities.

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