Changes in Potassium Concentration During Opioid Antagonist Induction: Comparison of Two Randomized Clinical Trials  

Oleh:

Badaras, Robertas ; Jovaisa, Tomas ; Judickas, Sarunas ; Ivaskevicius, Juozas

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Journal of Addiction Medicine vol. 10 no. 04 (Jul. 2016), page 244-247.
Topik: Anesthesia; Electrolyte Abnormalities; Hyperkalemia; Naltrexone; Opioid Detoxification

Ketersediaan

Perpustakaan FK Nomor Panggil: J06.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objectives: Opioid antagonist induction under general anesthesia or heavy sedation has been criticized due to its associated morbidity and mortality. Information on the potential causes of these complications is limited. We aimed to compare electrolyte concentration changes during rapid opioid antagonist induction under general anesthesia and conscious sedation, and to find out whether these changes are associated with cardiovascular complications. Methods: We used a pooled database analysis of 2 prospective randomized controlled clinical trials carried out in Lithuania between 2002 and 2014. Opioid-dependent patients underwent opioid antagonist induction under general anesthesia (n?=?50) or conscious sedation (n?=?68). Electrolyte levels were measured before the procedure, 3?hours after antagonist induction, and 3?hours after the end of the procedure. Results: General anesthesia was associated with initial hyperkalemia, which was followed by rapid reduction in potassium concentration (P?

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali