Ketoasidosis Diabetik di Diabetes Melitus Tipe 1  

Oleh:

Ridwan, Zuhrinah ; Bahrun, Uleng

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Indonesian Journal of Clinical Pathology and Medical Laboratory vol. 22 no. 02 (Mar. 2016), page 200-203.
Topik: Type 1 Diabetes Mellitus; Autoimmune; Diabetic Ketoacidosis; Blood Glucose; C-Peptide; Diabetes Melitus Tipe 1; Autoimun; Ketoasidosis Diabetik; Glukosa Darah
Fulltext: I01 v22 n2 p200 kelik2017.pdf (127.64KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: I01.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Type 1 Diabetes Mellitus (DMT1) is an autoimmune disease characterized by impaired carbohydrate, protein and lipid metabolism resulting in insulin deficiency either absolute or relative. The absolute insulin deficiency found in DMT1, is caused by a defect in the pancreatic ß cells leading to a defect in insulin synthesis by the pancreas gland. In this article, a case of type 1 DM in a child with ketoacidosis diabetes has been reported. The diagnosis was based on classical symptoms, blood glucose level, C-peptide, metabolic acidosis and keton uria. The case reported is a 12 year old girl, with main complaints of 9 kg body weight loss since three (3) years ago. The patient always felt hungry, thirsty and was frequently urinating. In her family history no such case was denied. The patient had been treated in the district general hospitals for five (5) days and was diagnosed as type 1 diabetes mellitus and was then referred to the Dr. Wahidin Sudirohusodo Hospital. The laboratory test results revealed as follows, random glucose level was 729 mg/dL, arterial blood gas analysis showed metabolic acidosis, C-peptide was 0.1 ng/mL and urinalysis showed 150 mg/dL protein, 1000 mg/dL glucose, 150 mg/ dL ketone and 250 RBC/uL. The patient was diagnosed as type 1 diabetes mellitus with diabetic ketoacidosis and received 0.5 U/kg/day insulin therapy. This case report aimed to determine the type 1 diabetes mellitus in a child is accompanied by diabetic ketoacidosis.

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