Effect of Tomato (Lycopersicum Commune) Juice on Vaginal Wall Elasticity in Menopausal Rats  

Oleh:

Prasetya, Arief Widya ; Widjayanti, Yhenti

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Folia Medica Indonesiana vol. 51 no. 2 (2015), page 132-136.
Topik: menopause; tomato juice; elastisity of the vaginal wall
Fulltext: download-fullpapers-fmi3bd64bffd6full.pdf (68.99KB)

Isi artikel

Menopausal period is a hipoestrogen condition. In menopausal periode, some woman get vaginal atrophy because of decreasing estrogen level. It can cause a decline of vagina elastisity. Tomatoe is known as rich of lignan phytoestrogen. Phytoestrogen can increase estradiol level on blood. However the effect of tomato juice toward the elastisity of vaginal wall of ovariectomized rattus is still unknown. The purpose of this research was to study the effect of tomato juice (Lycopersicum commune) toward elastisity of the vaginal wall of ovariectomized rattus. This study was a laboratory experiment using Post test Only One Control Group Design. This study used 24 female-ovariectomized Rattus norvegicus Wistar strain randomly divided into 4 groups, one control group (K) and three treatment groups three defference dosage of tomato juice that is 110 mg/kgBW/day (P1), 220 mg/kgBW/day (P2) and 330 mg/kgBW/day (P3) for 28 days. The results showed that there was an increaseof collagen synthesis in vagina wall of ovariectomized rattus. The Control group showed the lowest level of estradiol = 67.43% + 2.82., while the highest result was found on group P3 93.29% ± + 2.63. One -way ANOVA test showed a significant difference between control group and all treatment groups. Hence the study shows that the application of tomato juice indeed increase the elastisity of the vaginal wall during menopause. (FMI

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