Ectopic Pregnancy after In Vitro Fertilization: Differences between Fresh and Frozen-Thawed Cycles  

Oleh:

Londra, Laura ; Moreau, Caroline ; Strobino, Donna ; Garcia, Jairo ; Zacur, Howard ; Zhao, Yulian

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 104 no. 01 (Jul. 2015), page 110–118.
Topik: Ectopic Pregnancy; Embryo Transfer; In Vitro Fertilization; Risk Factors
Fulltext: F02 v104 n1 p110 kelik2016.pdf (507.9KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective: To evaluate whether the uterine environment is associated with the risk of ectopic implantation by comparing outcomes of fresh and frozen-thawed embryo transfers. Design: Retrospective historical cohort. Setting: Not applicable. Patient(s): We used the Society for Assisted Reproductive Technologies (SART) database to identify pregnancies that resulted from fresh and frozen blastocyst transfers from 2008 to 2011. Intervention(s): None. Main Outcome Measure(s): We determined the proportion of ectopic (EP) versus intrauterine-only pregnancies resulting from fresh or frozen embryo transfers in autologous and donor-oocyte cycles. Generalized estimation equation regression models were used to adjust for maternal and treatment characteristics. Result(s): Among 103,070 cycles that resulted in a clinical pregnancy, 1.38% were ectopic. The odds of EP were 65% lower in women who had a frozen compared with a fresh transfer in autologous cycles. Donor-oocyte transfers had lower odds of EP compared with autologous cycles, with no difference between fresh and frozen donor transfers. Women who had both a fresh and a frozen transfer with autologous oocytes had a higher risk of EP in their fresh cycles compared with their frozen cycles. Conclusion(s): Embryo transfers in cycles without ovarian hyperstimulation, such as frozen or donor cycles, were associated with lower rates of EP compared with fresh autologous cycles, suggesting that a difference in the tubal-uterine environment contributes to abnormal implantation after IVF.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali