Baby Budgeting: Oocyte Cryopreservation in Women Delaying Reproduction Can Reduce Cost Per Live Birth  

Oleh:

Devine, Kate ; Mumford, Sunni L. ; Goldman, Kara N. ; Hodes-Wertz, Brooke ; Druckenmiller, Sarah ; Propst, Anthony M. ; Noyes, Nicole

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 103 no. 06 (Jun. 2015), page 1446–1453.
Topik: Oocyte Cryopreservation; Vitrification; Fertility Preservation; Cost Analysis; ART
Fulltext: F02 v103 n6 p1446 kelik2016.pdf (821.58KB)

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Perpustakaan FK Nomor Panggil: F02.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Objective: To determine whether oocyte cryopreservation for deferred reproduction is cost effective per live birth using a model constructed from observed clinical practice. Design: Decision-tree mathematical model with sensitivity analyses. Setting: Not applicable. Patient(s): A simulated cohort of women wishing to delay childbearing until age 40 years. Intervention(s): Not applicable. Main Outcome Measure(s): Cost per live birth. Result(s): Our primary model predicted that oocyte cryopreservation at age 35 years by women planning to defer pregnancy attempts until age 40 years would decrease cost per live birth from $55,060 to $39,946 (and increase the odds of live birth from 42% to 62% by the end of the model), indicating that oocyte cryopreservation is a cost-effective strategy relative to forgoing it. If fresh autologous assisted reproductive technology (ART) was added at age 40 years, before thawing oocytes, 74% obtained a live birth, and cost per live birth increased to $61,887. Separate sensitivity analyses demonstrated that oocyte cryopreservation remained cost effective as long as performed before age 38 years, and more than 49% of those women not obtaining a spontaneously conceived live birth returned to thaw oocytes. Conclusion(s): In women who plan to delay childbearing until age 40 years, oocyte cryopreservation before 38 years of age reduces the cost to obtain a live birth. (Fertil Steril_ 2015;103:1446–53. _2015 by American Society for Reproductive Medicine.)

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