Functional Anatomy and Oncologic Barriers of the Larynx  

Oleh:

Mor, Niv ; Blitzer, Andrew

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Otolaryngologic Clinics of North America (keterangan: ada di ClinicalKey) vol. 48 no. 04 (Aug. 2015), page 533–545 .
Topik: Larynx; Tumor; Barriers; Facilitator; Inflammation

Ketersediaan

Perpustakaan FK Nomor Panggil: O06.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Laryngeal barriers to tumor spread are a product of laryngeal development, anatomic barriers, and enzymatic activity. Supraglottic and glottic/subglottic development is distinct and partially explains the metastatic behavior of laryngeal carcinoma. Dense connective tissues and elastic fibers provide anatomic barriers within the larynx. Laryngeal cartilage contains dense cartilage, enzyme inhibitors, and an intact perichondrium making it relatively resistant to tumor invasion; however, focal areas of vulnerability are created by ossified cartilage and natural interruptions in the perichondrium. Local inflammation and the enzymatic interplay between tumor and host are important factors in the spread of laryngeal tumor.

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