Assessment of rosacea severity: A review of evaluation methods used in clinical trials  

Oleh:

Hopkinson, Dennis ; Tuchayi, Sara Moradi ; Alinia, Hossein ; Feldman, Steven R.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: JAAD: Journal of the American Academy of Dermatology (keterangan: ada di ClinicalKey) vol. 73 no. 01 (Jul. 2015), page 138–143.
Topik: erythema; ocular rosacea; papules and pustules; phymatous rosacea; rosacea; scale; self-assessment; severity; telangiectasias; treatment

Ketersediaan

Perpustakaan FK Nomor Panggil: J15.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background Novel rosacea treatments are needed. Assessment methodologies for clinical trials of rosacea treatments are not standardized and are relatively inadequate. To determine the efficacy of new treatments, a valid and reliable assessment methodology is needed. Objective We sought to determine the assessment methodologies used in clinical trials for rosacea treatments, to demonstrate the need for a valid and reliable assessment tool, and to describe the relevant properties of such a tool. Methods PubMed and MEDLINE were searched for clinical trials of rosacea treatments since January 1, 1985. Results In all, 32 clinical trials met inclusion criteria. Assessment methodologies were highly variable, and standardized assessment methodologies were used in only 3 studies. The various manifestations of rosacea were assessed inconsistently. Limitations Eighteen articles could not be included as a result of lack of access to the full text. Conclusions The diverse methodologies make the assessment of novel treatments and comparison of treatments difficult. A valid and reliable assessment tool is needed to properly assess novel treatments to improve the management of rosacea.

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