Coexistence of autoimmune bullous diseases (AIBDs) and psoriasis: A series of 145 cases  

Oleh:

Ohata, Chika ; Ishii, Norito ; Koga, Hiroshi ; Fukuda, Shunpei ; Tateishi, Chiharu

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: JAAD: Journal of the American Academy of Dermatology (keterangan: ada di ClinicalKey) vol. 73 no. 01 (Jul. 2015), page 50–55 .
Topik: anti-laminin ?1 (p200) pemphigoid; autoimmune bullous disease; bullous pemphigoid; psoriasis; psoriasis vulgaris; pustular psoriasis

Ketersediaan

Perpustakaan FK Nomor Panggil: J15.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background Many case reports have described the coexistence of autoimmune bullous diseases (AIBDs) and psoriasis. Among them, anti-laminin ?1 (p200) pemphigoid is the best known. Objectives We sought to characterize patients with AIBDs and psoriasis and to investigate common AIBDs occurring in these patients. Methods This retrospective study included 145 patients with coexisting AIBD and psoriasis given a diagnosis from January 1, 1996, to July 31, 2013, at an academic dermatology department. Of these, 134 were consultation cases regarding AIBD diagnosis. Results Ratio of male to female patients was 5.7:1. Psoriasis onset preceded AIBD onset in most patients. Mean age at AIBD onset was 65.4 years, and mean duration between psoriasis and AIBD onset was 14.6 years. Most cases had single AIBD, whereas 16 cases had combined AIBDs. Bullous pemphigoid was the most prevalent (63.4%) followed by anti-laminin ?1 pemphigoid (37.2%). Limitations Consultation cases may not have included mild AIBD cases. Conclusion This study confirmed the association of psoriasis and anti-laminin ?1 pemphigoid. However, because bullous pemphigoid is a much more common disease, it is seen more frequently in patients with psoriasis than anti-laminin ?1 pemphigoid.

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