Prenatal Supplementation with Docosahexaenoic Acid Has No Effect on Growth through 60 Months of Age  

Oleh:

Gonzalez-Casanova, Ines ; Stein, Aryeh D ; Wei Hao ; Garcia-Feregrino, Raquel ; Barraza-Villarreal, Albino

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: JN: The Journal of Nutrition vol. 145 no. 06 (Jun. 2015), page 1330-1334.
Topik: child growth; child development; prenatal; supplementation; polyunsaturated fatty acids; maternal and child health; docosahexaenoic acid

Ketersediaan

Perpustakaan FK Nomor Panggil: J42.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background: Prenatal supplementation with docosahexaenoic acid (DHA) has been shown to increase birth size, but it is unclear whether these differences translate into improved postnatal growth. Objective: We assessed the effect of prenatal supplementation with DHA on offspring weight, length, and body mass index (BMI) through 60 mo of age. Methods: We examined growth patterns (height, weight, and BMI) in a cohort of 802 Mexican children whose mothers participated in a randomized, controlled trial of daily supplementation with 400 mg/d of DHA or a placebo from week 18–22 of gestation through delivery, with the use of a longitudinal multilevel model of growth. Results: Overall, means ± SDs of height-, weight-, and BMI-for-age z scores relative to WHO growth standards at 60 mo were -0.49 ± 0.91, -1.15 ± 1.07 and 0.13 ± 1.11, respectively. There were no significant differences by treatment group (all P > 0.05) for height, weight, or BMI at any age through 60 mo. Similarly, DHA did not affect the average growth or the trajectories for these measures through 60 mo. Conclusion: Prenatal DHA supplementation did not affect height, weight, or BMI through 60 mo of age.

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