The Risk of Type 1 Diabetes Among Offspring of Immigrant Mothers in Relation to the Duration of Residency in Sweden  

Oleh:

Hussen, Hozan Ismael ; Moradi, Tahereh ; Persson, Martina

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Diabetes Care vol. 38 no. 05 (May 2015), page 934-936.

Ketersediaan

Perpustakaan FK Nomor Panggil: D05.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

OBJECTIVE The risk for type 1 diabetes mellitus (T1DM) is increased in the second compared with the first generation of immigrants in Sweden. We investigated the effect of the mother’s duration of stay in Sweden on the risk of T1DM in the offspring. RESEARCH DESIGN AND METHODS Using data from national registries, we identified all subjects with T1DM among 984,798 children born in Sweden (aged 0–18 years) between 1992 and 2009. Incidence rate ratios (IRRs) with 95% CI were estimated using Poisson regression. RESULTS Offspring of mothers living in Sweden for up to 5 years had a 22% lower risk of T1DM (adjusted IRR 0.78, 95% CI 0.63–0.96) compared with offspring of mothers living in Sweden for 11 years or more. The risk increased with the mother’s duration of stay in Sweden. CONCLUSIONS Our findings support the hypothesis that immigration to Sweden is associated with exposure to new environmental factors that contribute to the development of T1DM in genetically susceptible individuals.

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