Surgical resection of peritoneal or thoracoabdominal wall implants from hepatocellular carcinoma  

Oleh:

Tekemura, N. ; Hasegawa, K. ; Aoki, T. ; Sakamoto, Y.

Jenis: Article from Article - diterbitkan di jurnal ilmiah internasional
Dalam koleksi: BJS: British Journal of Surgery vol. 101 no. 08 (Jul. 2014), page 1017-1022.
Topik: hepatocellular carcinoma; hepatic resection; liver transplantation; hepatitis b; hepatitis c; infections; hepatectomy; tumour implant; gastrointestinal cancer

Ketersediaan

Perpustakaan FK Nomor Panggil: B15.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Background Peritoneal or thoracoabdominal wall implants from hepatocellular carcinoma (HCC) occur occasionally after biopsy, percutaneous therapy or resection, and spontaneously, with no effective treatment available. The objective of this study was to clarify the indications for, and benefits of, surgical resection of such HCC implants. Methods This was a retrospective analysis of patients who underwent resection for peritoneal or chest wall implants from HCC over 14?years (1997–2011). Indications for surgery for implanted HCC were: limited number of implanted lesions including those found incidentally during surgery; intrahepatic lesion absent or predicted to be locally controllable; and absence of ascites with sufficient hepatic functional reserve. Prognostic factors affecting survival after resection were determined by univariable and multivariable analysis. Results A total of 32 patients underwent 36 resections. Cumulative 1-, 3- and 5-year overall survival rates were 71, 44 and 39 per cent respectively, with a median survival time of 34·5?months. Univariable and multivariable analysis revealed that poor perioperative intrahepatic disease control was associated with poor survival. Conclusion Surgical resection of implanted HCC may improve long-term survival in selected patients as long as intrahepatic disease is absent or well controlled.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali