Loop electrosurgical excision procedure and risk of miscarriage  

Oleh:

Ciavattini, Andrea ; Clemente, Nicolo ; Carpini, Giovanni Delli ; Gentili, Chiara

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 103 no. 04 (Apr. 2015), page 1043-1048.
Topik: Loop electrosurgical excision procedure; LEEP; miscarriage

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K Non-tandon: tidak ada Tandon: 1

Lihat Detail Induk

Isi artikel

Objective To evaluate the risk of miscarriage in the subsequent pregnancy after a loop electrosurgical excision procedure (LEEP), also considering time elapsed from LEEP to pregnancy. Design Multicenter, retrospective cohort study. Setting Tertiary care university hospitals. Patient(s) Women who had undergone LEEP from January 2000 to December 2011. Women with histologic assessment of low-grade cervical dysplasia, not requiring subsequent surgical treatment, constituted the control group. Intervention(s) None. Main Outcome Measure(s) The first pregnancy after the procedure was evaluated, and only women with singleton spontaneous pregnancies were considered. Women with time intervals of <12 months and women with intervals of =12 months or more from LEEP to pregnancy were then compared, to identify adjusted odds ratios for miscarriage. Result(s) In women previously treated with LEEP, a total of 116 cases of miscarriage (18.1%) was reported. The mean time interval from LEEP to pregnancy for women with miscarriage compared with women without miscarriage was significantly shorter (25.1 ± 11.7 months vs. 30.1 ± 13.3 months). A higher rate of miscarriage in women with a LEEP-to-pregnancy interval of <12 months compared with controls emerged (28.2% vs. 13.4%; adjusted odds ratio 2.60, 95% confidence interval 1.57–4.3). No significant difference in the rate of miscarriage in women with a LEEP-to-pregnancy interval of =12 months compared with controls emerged. Conclusion(s) Women with a time interval from LEEP to pregnancy of <12 months are at increased risk for miscarriage.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali