Is polycystic ovarian morphology related to a poor oocyte quality after controlled ovarian hyperstimulation for intracytoplasmic sperm injection? Results from a prospective, comparative study  

Oleh:

Sigala, Julien ; Sifer, Christophe ; Dewailly, Didier ; Robin, Geoffroy

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 103 no. 01 (Jan. 2015), page 112-118.
Topik: PCOS; PCOM; IVF; oocyte quality; oocyte morphology
Fulltext: PIIS0015028214022225.pdf (217.86KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K Non-tandon: tidak ada Tandon: 1

Lihat Detail Induk

Isi artikel

Objective To evaluate the relationship between polycystic ovarian morphology (PCOM) and oocyte quality after controlled ovarian stimulation for intracytoplasmic sperm injection (ICSI). Design Prospective, comparative study with concurrently treated and age-matched controls. Setting Academic IVF unit of the Lille University Hospital. Patient(s) A total of 194 women were prospectively included before their first IVF-ICSI attempt for exclusive male infertility. They were classified into PCOM (n = 97) or control groups (n = 97) according to their follicle number per ovary. The nuclear maturation and morphologic aspects of 1,013 oocytes from PCOM patients were assessed and compared with those of 774 oocytes from controls. Intervention(s) None. Main Outcome Measure(s) Rate of metaphase II (MII) and morphologically abnormal oocytes. Result(s) The mean number of total and MII oocytes retrieved was significantly higher in the PCOM group. The rate of MII and morphologically abnormal oocytes was equivalent between the two groups. The mean number of embryos was significantly higher in the PCOM group. However, the percentage of top-quality embryos on day 3 was similar between the two groups. The implantation and clinical pregnancy rates were significantly higher in the PCOM group. Conclusion(s) Polycystic ovarian morphology does not have a negative impact on the quality of oocytes and embryos or the outcome of IVF-ICSI.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali