Perfusion Imaging in the 3-hour Time Window Predicts a tPA-associated Hemorrhage in Acute Ischemic Stroke  

Oleh:

Rangaraju, Srikant ; Edwards, Adam ; Dehkharghani, Seena ; Nahab, Fadi

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Neurologist vol. 19 no. 03 (Feb. 2015), page 68–69.
Topik: tPA; tissue plasminogen activator; intracranial hemor-rhage; symptomatic ICH; CT perfusion; CT angiography

Ketersediaan

Perpustakaan FK Nomor Panggil: N06.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Perfusion imaging is being evaluated in acute ischemic stroke patients to identify those who may benefit from reperfusion therapies beyond the standard thrombolytic time window but limited data are available on its utility in patients presenting within the standard thrombolytic time window. We report a case of a patient presenting within the 3-hour time window where computerized tomographic perfusion imaging before intravenous thrombolysis identified a large volume of severely ischemic tissue and where intravenous tissue plasminogen activator administration subsequently resulted in a fatal intracerebral hemorrhage. Whether perfusion imaging can predict an increased risk of tissue plasminogen activator–associated symptomatic hemorrhage in patients presenting within the standard thrombolytic time window requires further study.

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