Anesthetic Neurotoxicity — Clinical Implications of Animal Models  

Oleh:

Rappaport, Bob A. ; Suresh, Santhanam ; Hertz, Sharon ; Evers, Alex S. ; Orser, Beverley A.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 372 no. 09 (Feb. 2015), page 796-797.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

General anesthetic and sedative drugs are administered to millions of infants, toddlers, and preschool children each year to facilitate life-saving surgery and other essential surgical or medical procedures. In the past two decades, mounting data from animal and observational human studies have raised concerns that general anesthetics may cause neurotoxic changes in the developing brain that lead to adverse neurodevelopmental outcomes later in life. To address the growing concern about the potential adverse consequences of general anesthesia in young patients, in 2009 the Food and Drug Administration (FDA) established a public–private partnership with the International Anesthesia Research Society (IARS) called Strategies for Mitigating Anesthesia-Related Neurotoxicity in Tots, or SmartTots.1

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