Long-term outcomes following microwave ablation for liver malignancies  

Oleh:

Leung, U. ; Kuk, D. ; D'Angelica, M.I. ; Kingham, T.P. ; Allen, P.J.

Jenis: Article from Article - diterbitkan di jurnal ilmiah internasional
Dalam koleksi: BJS: British Journal of Surgery vol. 102 no. 01 (Jan. 2015), page 85-91.
Topik: tumor; MWA; morbidity; mortality; kaplan-meier analysis; liver
Fulltext: bjs9649.pdf (593.8KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: B15.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Background Microwave ablation has emerged as a promising treatment for liver malignancies, but there are scant long-term follow-up data. This study evaluated long-term outcomes, with a comparison of 915-MHz and 2·4-GHz ablation systems. Methods This was a retrospective review of patients with malignant liver tumours undergoing operative microwave ablation with or without liver resection between 2008 and 2013. Regional or systemic (neo)adjuvant therapy was given selectively. Local recurrence was analysed using competing-risk methods with clustering, and overall survival was determined from Kaplan–Meier curves. Results A total of 176 patients with 416 tumours were analysed. Colorectal liver metastases (CRLM) comprised 81·0 per cent of tumours, hepatocellular carcinoma 8·4 per cent, primary biliary cancer 1·7 per cent and non-CRLM 8·9 per cent. Median follow-up was 20·5?months. Local recurrence developed after treatment of 33 tumours (7·9 per cent) in 31 patients (17·6 per cent). Recurrence rates increased with tumour size, and were 1·0, 9·3 and 33 per cent for lesions smaller than 1?cm, 1–3?cm and larger than 3?cm respectively. On univariable analysis, the local recurrence rate was higher after ablation of larger tumours (hazard ratio (HR) 2·05 per cm; P?

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali