Slowly progressive pure dysgraphia with late apraxia of speech: A further variant of the focal cerebral degeneration  

Oleh:

Luzzi, Simona ; Piccirilli, Massimo

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Brain and Language (Full Text) vol. 87 no. 3 (2003), page 355-360.
Topik: Progressive dysgraphia; Central agraphia; Graphemic buffer; Spelling disorders; Apraxia of speech; Non-fluent aphasia; Focal cerebral degeneration; Focal atrophy; Alzheimer's disease; Frontotemporal dementia
Fulltext: 87_03_Luzzi.pdf (119.0KB)

Isi artikel

We report a longitudinal neuropsychological investigation of a patient with slowly progressive pure dysgraphia. Cognitive analysis of writing errors suggested a selective impairment of the graphemic buffer. After about seven years, the patient developed an apraxia of speech. No other linguistic or generalized cognitive impairment occurred subsequently, so that, twelve years after the beginning of the disease, the patient showed complete independence in daily life and still remained professionally active. Functional neuroimaging revealed hypoperfusion confined to left fronto-temporal lobe. This well-recognizable syndrome does not fit any of the cases described previously in the literature. This report therefore, adds another variant to heterogeneous clinical spectrum of focal neurodegenerative disorders, further suggesting the opportunity of their distinction from pathological processes leading to dementia.

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