Lateralized effects of subthalamic nucleus stimulation on different aspects of speech in Parkinson's disease  

Oleh:

Santens, Patrick ; Letter, Miet De ; Borsel, John Van ; Reuck, Jacques De ; Caemaert, Jacques

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Brain and Language (Full Text) vol. 87 no. 2 (2003), page 253-258.
Topik: Parkinson; STN stimulation; Lateralization; Prosody; Articulation; Intelligibility; Voice; Loudness; Speech rate; Basal ganglia
Fulltext: 87_02_Santens.pdf (213.54KB)

Isi artikel

In this report, we have analyzed the effects of left and right STN stimulation separately on different aspects of speech. Significant differences were found between left and right stimulation. It appears that selective left-sided stimulation has a profoundly negative effect on prosody, articulation and hence intelligibility. Right-sided stimulation does not display this side-effect. There is no significant difference in speech characteristics between bilateral stimulation on and off. We suggest that a balanced tuning of bilateral basal ganglia networks is necessary for speech, and that the left circuit is probably dominant.

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