Perioperative Management of the Opioid Tolerant Patient for Orthopedic Surgery  

Oleh:

Mahathanaruk, Marchyarn ; Hitt, James ; LeonCasasola, Oscar A. de

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Anesthesiology Clinics (keterangan: ada di ClinicalKey) vol. 32 no. 04 (Dec. 2014), page 923–932 .
Topik: Opioid tolerance; Cellular mechanisms; Postoperative pain; Opioids; Ketamine

Ketersediaan

Perpustakaan FK Nomor Panggil: A34.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The prevalence of opioid use in the North America and some countries of the European Union has resulted in an increase in the number of patients who may exhibit opioid tolerance when requiring postoperative pain management. The approach to postoperative pain control in these patients is different from the strategies used in opioid-naïve patients. Better understanding of the cellular mechanisms of opioid tolerance in animals has resulted in the transfer of these concepts from the basic research to the clinical arena. This article presents new developments in opioid tolerance and how this knowledge can be applied to clinical practice.

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