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The role of neuronal signaling in controlling cerebral blood Xow
Oleh:
Drake, Carrie T.
;
Iadecola, Costantino
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
Brain and Language (Full Text) vol. 102 no. 2 (2007)
,
page 141-152.
Topik:
Functional hyperemia
;
Cerebral blood Xow
;
Neurovascular unit
;
BOLD
Fulltext:
102_02_Drake.pdf
(369.47KB)
Isi artikel
Well-regulated blood Xow within the brain is vital to normal function. The brain’s requirement for suYcient blood Xow is ensured by a tight link between neural activity and blood Xow. The link between regional synaptic activity and regional cerebral blood Xow, termed functional hyperemia, is the basis for several modern imaging techniques that have revolutionized the study of human brain activity. Here, we review the mechanisms of functional hyperemia and their implications for interpreting the blood oxygen level-dependent (BOLD) contrast signal used in functional magnetic resonance imaging (fMRI).
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