Preliminary evidence for impaired rapid verb generation in schizophrenia  

Oleh:

Woods, Steven Paul ; Weinborn, Michael ; Posada, Carolina ; O’Grady, Joy

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Brain and Language (Full Text) vol. 102 no. 1 (2007), page 46-51.
Topik: Schizophrenia; Neuropsychology; Cognitive processes; Verbal Xuency; Verbs
Fulltext: 102_01_Woods.pdf (218.3KB)

Isi artikel

It has been hypothesized that nouns and verbs are processed within relatively separable semantic memory networks. Although abnormal semantic processing is a common feature of schizophrenia-spectrum disorders, no prior studies have speciWcally examined the comparability of noun and verb generation deWcits in schizophrenia. In the current study, verb (action), noun (animal), and letter (f) Xuency performance was evaluated in 22 inpatients with schizophrenia and 27 healthy comparison subjects. On average, individuals with schizophrenia performed approximately one standard deviation below the healthy comparison subjects on action, animal, and letter Xuency. Action Xuency—but not letter or animal Xuency—was moderately correlated with tests of working memory, response inhibition, semantic memory, and cognitive Xexibility. Findings suggest that verb- and noun-based Xuency deWcits are of comparable severity in schizophrenia, but that the impairment in verb generation may be driven by diVerent underlying cognitive mechanisms. Further, hypothesis-driven research on the nature and extent of verb network disruption in schizophrenia appears warranted.

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