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Komplikasi Psoriasis pada Sendi atau Artritis Psoriatika
Oleh:
Eko, Vincea
Jenis:
Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi:
Cermin Dunia Kedokteran vol. 41 no. 05/216 (May 2014)
,
page 352-355.
Topik:
Psoriatic arthritis
;
HLA gene
;
CD8
;
arthrocentesis
;
spondylitis
;
DIP
;
arthritis mutilans
;
rheumatoid arthritis
;
NSAIDs
;
cyclosporine
;
methotrexate
Fulltext:
10_216.pdf
(607.41KB)
Ketersediaan
Perpustakaan FK
Nomor Panggil:
C04.K.2014
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Psoriatic arthritis is a chronic disease with specifi c lesion of psoriasis and later arthritis. This disease has a strong genetic inheritance, several involved genes are HLA-Cw6, B27, B38. Psoriatic arthritis also has dominant CD8 Tcells. Several types of psoriatic arthritis are: Symmetric arthritis, Assymetric arthritis, Distal Inter Phalangeal (DIP), Spondylitis, Arthritis mutilans. Around 80% psoriatic arthritis preceded by skin lesions, and in around 15% arthritis precede the skin lesions, making psoriatic arthritis hard to diagnose. Arthrocentesis can aid diagnosis and also as an adjunctive therapy. Unlike rheumatoid arthritis, psoriatic arthritis doesn’t have specifi c antibody, so the main therapy in psoriatic arthritis is not steroid but NSAIDs, sulfasalazine and cyclosporine, lefl unomide, methotrexate. The progonosis depends on age at onset, stadium, diagnosis and accurate treatment, and number of joints involved.
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