Leptin, Adiponectin and Resistin Concentration in Obesity Class I and II at Sardjito Hospital Yogyakarta  

Oleh:

Sinorita, Hemi ; Asdie, Rizka H. ; Pramono, R. Bowo ; Purnomo, Luthfan B. ; Asdie, AH.

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Acta Medica Indonesiana vol. 42 no. 2 (Apr. 2010), page 74-77.
Topik: leptin; adiponectin; resistin; obesity class I and II.
Fulltext: leptin.pdf (51.43KB)

Isi artikel

Aim: to determine the level of different concentration of leptin, adiponectin and resistin among obesity class I and class II population. Methods: cross sectional study was conducted from June 2006 until January 2007 on 57 patients with obese diabetic and non diabetic Native avanese. They were divided into obese class I (body mass index [BMI] >25 kg/m2 to <30 kg/m2) and obese class II (BMI >30 kg/m2). Leptin, adiponectin and resistin level concentration were measured. Results: leptin concentration in obese class I was 13,998 ± 13,486 ng/ml; adiponectin was 3.98 ± 1.78 µg/ml; resistin were 25.676 ± 13.434 ng/ml. Leptin concentration in obese class II 31,074 ± 26,158 ng/ml; adiponectin 4,75 ± 1,88 µg/ml; resistin 25,46 ± 12,26 ng/ml. Leptin concentration was significantly higher in obese class II than obese class I (p=0,002) and there was a positive weak correlation between BMI and leptin level, with Spearman correlation {coefficient correlation 0.363 (p=0.006)}. Adiponectin and resistin concentration was not significantly higher in obese class II than obese class I (p=0,156 and p=0,956). Conclusion: leptin concentration in obese class II was significantly higher than in obese class I but adiponectin and resistin were not different.

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