Prevalence of polycystic ovary syndrome in adolescents  

Oleh:

Christensen, Shawna B. ; Black, Mary Helen ; Smith, Ning ; Martinez, Mayra M. ; Jacobsen, Steve J.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 100 no. 02 (Aug. 2013), page 470-477.
Topik: Adolescence; body weight; childhood; epidemiology; obesity; polycystic ovary syndrome

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2013.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To investigate the prevalence of polycystic ovary syndrome (PCOS) in adolescents and its association with obesity. Design Cross-sectional study using electronic medical records. Setting Not applicable. Patient(s) Adolescents aged 15–19 years (n = 137,502). Intervention(s) None. Main Outcome Measure(s) PCOS diagnosed or defined according to National Institutes of Health (NIH) criteria. Result(s) The prevalence of a confirmed diagnosis of PCOS was 0.56%, which increased to 1.14% when undiagnosed cases with documented symptoms qualifying for PCOS according to NIH criteria were included. Compared with normal/underweight girls, the odds ratios (OR and 95% confidence interval [CI]) for confirmed PCOS diagnosis were 3.85 (3.04–4.88), 10.25 (8.16–12.84), and 23.10 (18.66–28.61) for overweight, moderately obese, and extremely obese adolescents, respectively, after adjusting for potential confounders. When adolescents with two or more supportive diagnoses were included (diagnosed and undiagnosed PCOS-NIH), the ORs (95% CI) for PCOS-NIH by weight class were significantly attenuated to 2.95 (2.53–3.44), 6.73 (5.78–7.83), and 14.65 (12.73–16.86) for overweight, moderately obese, and extremely obese adolescents, respectively. Conclusion(s) Overweight and obesity were associated with higher odds of PCOS in adolescents. Studies based solely on diagnosis codes may underestimate the prevalence of PCOS and overestimate the magnitude of the association between obesity and PCOS.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali