Ovarian damage after laparoscopic endometrioma excision might be related to the size of cyst  

Oleh:

Tang, Yan ; Chen, Shi-ling ; Chen, Xin ; He, Yu-Xia ; Ye, De-Sheng

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 100 no. 02 (Aug. 2013), page 464-469.
Topik: Endometrioma; excision; IVF; laparoscopy; retrieved oocytes

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2013.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective To investigate the relationship between the size of an excised endometrioma and the magnitude of damage to the ovary after the surgery. Design A retrospective, controlled study. Setting A university hospital. Patient(s) Eighty-five women with a history of laparoscopic excision of unilateral endometrioma who underwent in vitro fertilization (IVF). Intervention(s) IVF-embryo transfer procedures. Main Outcome Measure(s) Antral follicle counts (AFC), number of dominant follicles (follicles =15 mm), and number of oocytes retrieved. Result(s) In the group with cyst diameters of =4 cm and group with cyst diameters of <4 cm, the AFC, number of dominant follicles, and number of oocytes retrieved were decreased in the operated ovaries when compared with those in intact ovaries; in the former group, a statistically significant reduction was observed. The differences of AFC, number of dominant follicles, and number of oocytes retrieved from both ovaries were further compared among the two groups: the decrease in the group with cyst diameters of =4 cm was higher than in the group with cyst diameters of <4 cm. After adjusting for age and AFC in intact ovaries, similar results were obtained, although AFC only showed a tendency. In addition, the receiver operating characteristic curve analysis revealed a statistically significant, positive correlation between the size of excised cysts and the incidence of fewer than four oocytes retrieved from an operated ovary. Conclusion(s) The magnitude of the ovarian damage after laparoscopic endometrioma excision might be related to the size of cyst; the damage to ovaries is more severe when an endometrioma =4 cm is excised.

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