Phenotypic comparison of Caucasian and Asian women with polycystic ovary syndrome: a cross-sectional study  

Oleh:

Wang, Erica T. ; Chia-Ning Kao ; Shinkai, Kanade ; Pasch, Lauri ; Cedars, Marcelle I.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 100 no. 01 (Jul. 2013), page 214-218.
Topik: Ethnicity; hirsutism; polycystic ovary syndrome

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2013.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To determine whether manifestations of polycystic ovary syndrome (PCOS), particularly androgen excess, differ between Caucasian and Asian women in the San Francisco Bay Area. Design Cross-sectional study. Setting Multidisciplinary PCOS clinic at a tertiary academic center. Patient(s) 121 Caucasian and 28 Asian women, aged 18–44, examined between 2006 and 2011 with PCOS verified by a reproductive endocrinologist and dermatologist according to the Rotterdam criteria. Intervention(s) Transvaginal ultrasounds, comprehensive dermatologic exams, and serum testing. Main Outcome Measure(s) Hirsutism defined as a modified Ferriman-Gallwey (mFG) score =8, acne, androgenic alopecia, and biochemical hyperandrogenism. Result(s) Caucasian and Asian women had a similar prevalence of all measures of androgen excess. Both groups had similar total mFG scores and site-specific mFG scores, except Asian women had a lower site-specific mFG score for the chest. Although Asian women were more likely to use laser hair removal, the results were unchanged when the women with a history of laser hair removal were excluded. Conclusion(s) Caucasian and Asian women with PCOS living in the same geographic region had a similar prevalence of hirsutism as well as other markers for androgen excess. Further studies are necessary to evaluate the need for ethnic-specific mFG scores in women with PCOS.

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