Gangguan Imunodefisiensi Primer (PID)  

Oleh:

Kusumo, Pratiwi Dyah

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Widya: Majalah Ilmiah vol. 27 no. 324 (Oct. 2012), page 14-22.
Topik: Imunodefisiensi Primer (PID)
Fulltext: 14-22 - Bernard.pdf (6.62MB)

Isi artikel

Primary Immunodeficiency Disease (PID) is rare disorder in adult NS most often serious forms are detected during infancy or childhood. Recently the incidents of PID are increasing, that we have to be aware especially to the children. The objective of this writing is to discuss the Primary immunodeficiency disorder (PIDs) which are broadly classified as disorders of adaptive immunity (i.e.,T-cell, B-cell or combined immunodeficiencies) or of innate immunity (e.g. phagocyte and complement disorders) and usually attacts the children. The method used library research and the data are analized descriptively. It can be concluded that: (1) Although the clinical manifestations of PIDs are highly variable, most disorders involve at least an increased susceptibility to infection. (2) The failure to thrive; poor response to prolonged use of antibiotics; persistent thrush or skin abscesses; or a family history of PID (3) The application of mutation analysis is becoming an integral part of the complete evaluation of patients with primary immunodefiency (4) PIDs should be suspected in patients with: recurrent sinus or ear infections or pneumonias within a 1 year period.

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