Pengaruh Pb-asetat terhadap Berat dan Volume Testis Mencit Effect of Pb-acetate on Testicle Weight and Volum of Mice  

Oleh:

Isradji, Israhnanto

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Sains Medika (Jurnal Kedokteran dan Kesehatan) vol. 03 no. 02 (Jul. 2011), page 150-156.
Topik: Pb-acetate; testis weight; testicular volume.
Fulltext: Pengaruh Pb-asetat.pdf (138.4KB)

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Perpustakaan FK Nomor Panggil: S11.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Background: The human effort to meet the needs of human life is almost always cause pollution in theenvironment of his life. One of the pollutants that harm human beings are lead (Pb = plumbum), Pb is one ofthe heavy metals that are harmful to health. Pb may also affect the reproductive organs. The purpose of thisstudy to determine the effect of Pb-acetate on mouse testis weight and volumeDesign and Method: Eighty male mice placed in individual cages according to the group. Food and drinkprovided ad libitum. The treatment of male mice given for 6 weeks. Treatment with 0.2 ml distilled water toPI, P II were given a solution of 400 ppm Pb acetate total of 0.2 ml, P III was given a solution of 1000 ppm Pbacetate as many as 0.2 ml, and P IV were given a solution of 2000 ppm Pb acetate total of 0,2 ml by usinga gastric sonde, every morning once a day for 42 days. At week 7, mice were surgery to take the testis.Testicular volume was measured and weighed. Data were analyzed by ANOVA, hypothesis is accepted whenp<0.05, to know the difference between the effect of treatment used the least smallest difference test.Result: The weight of the testes treated with Pb-acetate 0 ppm, 400 ppm 1000 ppm and 2000 ppm consecutiveis 0.237, 0.237, 0.227 and 0.217 g, Volume testes treated with Pb acetate concentrations of 0 ppm, 400ppm 1000 ppm and 2000 ppm consecutive is 0.278, 0.273, 0.255 and 0.263 cm3, respectively testicularvolume Anova test results obtained by the probability of 0.189 (> 0.05), testis weight obtained by ANOVA testprobability of 0.216 (> 0.05), mean Pb -acetate had no effect on testis weight and volume.Conclusion: Pb-acetate had no effect on testis weight and volume (Sains Medika, 3(2):150-156).

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