Pengaruh Pemberian Minyak Jinten Hitam (Nigella sativa L.) Terhadap Volume Adenokarsinoma Mammae Secara In Vivo Studi Eksperimental Mencit galur C3H yang Diinokulasi Jaringan Tumor Effect of Jinten Hitam Seeds Oil (Nigella sativa L.) In adenocarsinoma Ma  

Oleh:

Suprijono, Agus ; Sumarno ; Hanugalih

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Sains Medika (Jurnal Kedokteran dan Kesehatan) vol. 03 no. 02 (Jul. 2011), page 129-134.
Topik: Jinten Hitam Oil (Nigella Sativa L.); Adenocarcinoma Mammae; Volume.
Fulltext: Minyak Jinten Hitam.pdf (142.92KB)

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Perpustakaan FK Nomor Panggil: S11.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background: Jinten hitam (Nigella sativa L.) oil is a liquid made from Jintem hitam seeds which has beenknown to contain Thymoquinone having anti-cancer efect. Many cancer patients turn to cheaper alternativetherapy including the traditional therapy. The objective of this experimental was to evaluate anti-cancereffect of Jinten hitam seeds oil in adenocarsinoma mammae C3H mice.Design and Methods: In this xperimental research with pre post test randomized control group design for21 days, 24 C3H mice with tumor were divided into 4 group. K-I serves as a control given standard diet andaquades, K-II given standard diet, aquades and first dose of Jinten Hitam oil (0.1 ml/days), K-III given standarddiet, aquades and second dose of Jinten Hitam oil ( 0.2 ml/days) and K-IV given standard diet, aquades andthird dose of Jinten Hitam oil ( 0.3 ml/days). The volume was recorded at the day 21.Results: mean of the effect of Jinten hitam oil effect in adenocarcinoma mammae for the four group were158.83 mm³, 259.73 mm³, 191.13 mm³, K-IV 126.27 mm³ respectively. Pair t-test and Wilcoxon test showedsignificant difference between First dose pre-First dose post and Second dose pre-second dose-post (p<0.05)and Anova test showed no significant difference between K-I K-II, K-I K-III, K-I K-IV, K-II K-III, K-II K-IV, K-III K-IV(p>0.05).Conclusion: Jinten Hitam oil has effect on the volume of Adenocarcinoma mammae in C3H mice (SainsMedika, 3(2):129-134).

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