Clinical Analysis of 50 Chinese Patients with Aqueous Misdirection Syndrome: a Retrospective Hospital-based Study  

Oleh:

Zhou, C. ; Qian, S. ; Yao, J. ; Tang, Y.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Journal of International Medical Research vol. 40 no. 04 (Jul. 2012), page 1568-1579.
Topik: Aqueous Misdirection Syndrome; Pars Plana Vitrectomy; Vitrectomy-Zonulectomy-Iridectomy; Best-Corrected Visual Acuity; Intraocular Pressure

Ketersediaan

Perpustakaan FK Nomor Panggil: J11.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

OBJECTIVES: To evaluate the efficacy of treatments for aqueous misdirection syndrome and explore possible risk factors influencing prognosis. METHODS: Data including demographics, initial clinical characteristics and ocular outcomes at follow-up were collected for patients treated for aqueous misdirection syndrome. Main outcome measures were: best-corrected visual acuity (BCVA); intraocular pressure (IOP); number of antiglaucoma medications; recurrence; complications. RESULTS: Data were available for 50 patients (57 eyes). Final mean BCVA improved significantly and correlated with baseline BCVA (mean follow-up, 34.47 ± 28.65 months). Final mean IOP and mean number of antiglaucoma medications were significantly reduced. Treatment failure rates were higher in patients with significantly higher IOP at baseline and/or shorter axial length. Following pars plana vitrectomy (PPV), recurrence occurred in two of 10 pseudophakic and one of 40 phakic eyes; complications were observed in 12/50 eyes (choroidal detachment, corneal decompensation, retinal detachment, vitreous haemorrhage, hyphaema). CONCLUSIONS: PPV and laser treatments, augmented by pharmacotherapy, were effective in treating aqueous misdirection syndrome. Surgical intervention should be undertaken early in eyes with higher baseline IOP and/or shorter axial length. Total vitrectomy-zonulectomy-iridectomy is a potential approach for recalcitrant cases.

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