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ArtikelAntioxidant Activity and Anticarcinogenic Properties of "Sisik Naga" (Drymoglossum piloselloides Presl.)  
Oleh: Endrini, Susi
Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Jurnal Kedokteran YARSI vol. 17 no. 02 (May 2009), page 89-92.
Topik: MTT assay; "sisik naga"; MCF-7; Antioxidant activity; cytotoxic properties
Fulltext: J51 v17 n2 2009 p89.pdf (1.34MB)
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Isi artikelThe research was conducted to determine the anticarcinogenic properties of "sisik naga" (Drymoglossum piloselloides Presl), by the micrculture tetrazolium salt (MTT) assay on the human breast carcinoma dependent hormone (MCF-7) cell lines. The preliminary result showed that the "sisik naga" extract displayed the cytotoxic effects against MCF-7 with IC50-calue of 83.63ug/ml. The antioxidative activity of the extracts which could contribute to their cytotoxic properties was also studied. The "sisik naga" extract was found to have high antioxidant activity with IC50-value of 4.229 ppm. The strong cytotoxic properties of the "sisik naga" extract could be due to its high antioxidant activity.
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