Computed tomography fi ndings of retinoblastoma patients at Cipto Mangunkusumo Hospital Jakarta  

Oleh:

Asih, Dewi ; Gatot, Djayadiman ; Sitorus, Rita S.

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Medical Journal of Indonesia vol. 18 no. 4 (Oct. 2009), page 239-243.
Topik: leukocoria; enhancement; calcifi cation
Fulltext: Volume 18, Issue 4, October 2009 - Computed tomography fi ndings of retinoblastoma patients at Cipto Mangunkusumo Hospital Jakarta.pdf (195.12KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: M35.K.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Aim As data of CT fi ndings for retinoblatoma in Indonesia is not yet available, this study aimed to determine patient distribution and to describe CT fi ndings of RB patients at Cipto Mangunkusumo Hospital. Methods From April 2004 to August 2007, CT scans were performed on 64 new patients of RB with clinical fi ndings: leukocoria (19 patients), leukocoria with proptosis (41 patients), buphthalmus (2 patients) and red eyes (2 patients). The CT scan was performed using single slice CT scan and multislice CT scan with axial and coronal section. The cases were categorized into 3 groups: grade I: tumor confi ned to the globe, grade II: tumor extended to orbital soft tissue or involved the optic nerve, and grade III: tumor extended beyond the orbit or intracranial space. The CT features were evaluated in each group for the presence of calcifi cation, contrast enhancement and lateralization. Results Sixty four patients (30 females and 34 males) were evaluated. Age range: 3 months up to 9 years old; bilateral 20 patients, unilateral 44 patients. Six patients of 19 patients with clinical fi nding leukocoria were included in group I, and the remaining were included in group II. Twenty seven patients of 41 patients with proptotic eyes were included in group II, and the remaining were included in group III. Patients with clinical fi nding buphthalmus and red eyes were included in group II. All of the group I tumors (6 patients) showed calcifi cation and enhancement. In group II (44 patients), calcifi cation was detected in 41 patients, and there was no evidence of contrast enhancement in 6 patients. Group III (14 patients): no calcifi cation in 2 patients, all of the tumors showed enhancement. Conclusion Our study showed calcifi cation in 92% of RB. Calcifi cation was not a favorable prognostic sign, because calcifi cation was detected in almost all of the extraocular and intracranial tumors. Tumor enhancement was not correlated with extra ocular tumor extension. The fi nding of leukocoria without proptosis could not exclude the presence of extraocular tumor extension. Suspicious intracranial invasion should be considered in proptotic RB patient. Most retinoblastoma cases in Indonesia are diagnosed at advanced stage, so that the objective of the therapy is life saving rather than visual salvation Key words: leukocoria, enhancement, calcifi cation

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali