The New World of DNA; Human Genomics  

Oleh:

[s.n]

Jenis: Article from Bulletin/Magazine
Dalam koleksi: The Economist (http://search.proquest.com/) vol. 404 no. 8801 (Sep. 2012), page 67-68.
Topik: Deoxyribonucleic acid--DNA; Genomes; Genomics; Research; Cellular Biology; Human Body

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Perpustakaan Pusat (Semanggi) Nomor Panggil: EE29.73 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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ENCODE stands for Encyclopedia of DNA Elements. The consortium that created it--442 members in 32 institutes around the world--has used the increasingly impressive tools available for sequencing genomes to mount a systematic analysis of 147 different types of human cell, attempting to say just what each part of the genome is doing in them. Their results confirm on a grand scale what has become clear over the decade since the Human Genome Project first produced a sequence of the three billion "letters" of which the genome is made: there is a great deal more to genomes than their genes. ENCODE has shown that fully three-quarters of the genome is transcribed into RNA at some stage in at least one of the body's different types of cell. All this RNA has a wide variety of uses. Whereas 62% of the genome may be turned into finished transcripts in some cell or other, only about 22% of the DNA ends up in such transcripts in the typical cell. Spectacularly sensitive as they are, the techniques used by ENCODE and other cutting-edge research still need to take material from many cells in order to put together a picture.

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