Eosinophilic Granuloma (Langerhans Cell Histiocytosis) Involving Neck and Mediastinal Lymph Nodes: a case report and its aspiration biopsy cytology  

Oleh:

Hastuti, Neni Wahyu ; Lubis, Humairah Medina Liza

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Cermin Dunia Kedokteran vol. 39 no. 04/192 (Apr. 2012), page 270-273.
Topik: Langerhans’ cell histiocytosis
Fulltext: 11_192Eosinophilic Granuloma.pdf (821.65KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: C04.K.2012 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Langerhans’ cell histiocytosis (LCH) is a prolif-erative histiocytic disorder of unknown cause originating from dendritic cells,8 with an esti-mated incidence of one to two cases per mil-lion population.1 The disease mostly occurs in individuals aged 21 to 69 years, with a mean age of 32 years.3 It belongs to a group of dis-orders with common primary event of accu-mulation and infiltration of monocytes, mac-rophages, and dendritic cells into the aff ected tissues. Its clinical presentation varies greatly, with symptoms ranging from mild to severe. The pathogenesis of LCH is not well under-stood and an optimal therapeutic strategy has yet to be established. LCH is a rare disease with multiple clinical features; only histologic examination and immunohistochemical as-says can lead to a final diagnosis

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