Father Figures; Genetic Damage and Paternal Age  

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Jenis: Article from Bulletin/Magazine
Dalam koleksi: The Economist (http://search.proquest.com/) vol. 404 no. 8799 (Aug. 2012), page 64.
Topik: Mutation; Genetic Testing; Aging; Paternity; Research

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Perpustakaan Pusat (Semanggi) Nomor Panggil: EE29.73 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Women have to get their reproducing done early. The menopause curtails it, and even before that a woman's fertility falls significantly over the years. Men--those who can find willing partners, at least--do not suffer in quite the same way, as many stories of celebrity elder fathers testify. But perhaps such ageing Lotharios should think twice, for evidence is accumulating that their offspring are at greater-than-average risk of genetic disease. The latest study to this effect has just been published in Nature by Kari Stefansson and his colleagues at deCODE Genetics, a genetic-analysis company based in Reykjavik that was founded to take advantage of Iceland's excellent medical records and its unique genealogical history. Dr Stefansson and his colleagues examined 78 trios of father, mother and child who are all still alive. In some cases they looked at grandchildren as well. Their goal was to examine the number of new mutations--traits not found in the normal body cells of either parent--in children. The average answer is about 63.

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