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BukuHubungan status perkawinan, APOE e4, dan jenis aktivitas fisik terhadap penurunan kognitif pada lansia perempuan (artikel Jurnal Neurona Vol.36 No.2 Maret 2019)
Bibliografi
Author: Singgih, Nicholas Andrian ; Turana, Yuda ; Handajani, Yvonne Suzy ; Widjaja, Nelly Tina ; Suryakusuma, Linda
Topik: APOE; cognitive decline; elderly; marital status; physical activity; JABFUNG-FKIK-YDT-2021-48
Bahasa: (ID )    
Penerbit: Departemen Neurologi FKUI/ RSUPN Dr. Cipto Mangunkusumo     Tempat Terbit: Jakarta    Tahun Terbit: 2019    
Jenis: Article - diterbitkan di jurnal ilmiah nasional
Fulltext: B48 Jurnal ilmiah Nasional Terakreditasi Kemenristekdikti peringkat 1 dan 2.pdf (3.16MB; 8 download)
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Abstract
Introduction: The number of elderly population in Indonesia continues to increase every year, especially women. Elderly women are at higher risk of experiencing decreased cognitive function.
Aims: To determine the relationship between the characteristics of the subject, vascular risk factors, APOE e4 genotype, and the type of physical activity with the decline of cognitive function in elderly women.
Methods: A cognitive cohort study of 114 elderly women who had been observed for a mean of ±2.5 years, as part of the Active Aging study at Atma Jaya Catholic University. The independent variables of this study included were age, education, marital status, vascular risk factors (hypertension, diabetes, dyslipidemia, and BMI), APOE e4, and types of physical activity. Cognitive function is measured using Mini Mental State Examination (MMSE).
Results: There were 114 subjects with mean age was 71.22±7.297 and 33.3% experienced a decline in cognitive function. There were 114 subjects with mean age was 71.22±7.297 and 33.3% experienced a decline in cognitive function. Age, marital status (single), and type of physical activity (cooking) have a significant relationship with Relative Risk (RR) of 4,45; 0,12; and 0,334.
Discussions: Factors related to cognitive decline in elderly women were age. Marital status (single) and cooking activities were protective factors.
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