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Detail
BukuBlood Pressure Variability and Cognitive Impairment in Acute Ischemic Stroke Patients (presented at 10th Scientific Meeting of Indonesian Society of Hypertension, Jakarta, 12-14 February 2016)
Bibliografi
Author: Sani, Tara Puspitarini ; Andrian, Yonathan ; Subrata, Irene Halim ; Suryakusuma, Linda ; Turana, Yuda
Topik: Blood pressure variability; post-stroke cognitive impairment; acute ischemic stroke; JABFUNG-FKIK-YDT-2021-71
Bahasa: (EN )    
Penerbit: Indonesian Society of Hypertension     Tempat Terbit: Jakarta    Tahun Terbit: 2016    
Jenis: Poster - pada seminar nasional
Fulltext: B71 Prosiding Poster Nasional.pdf (2.2MB; 3 download)
Abstract
Background: Vascular risk factors have significant impact on post-stroke cognitive impairment. Blood pressure variability has emerged as a novel vascular risk factor to affect cognitive functions.

Objective : Defining relation between blood pressure variability (BPV) and cognitive impairment in acute ischemic stroke patients.

Methods : This is a cross-sectional, retrospective study. Inclusion: Stroke patients admitted to Atma Jaya Hospital during first seven days after onset, age >= 18. Exclusion: death endpoint, NIHSS >= 15, aphasia. We evaluated Blood Pressure (BP) of acute ischemic stroke patients 4 times per day. Blood Pressure variability (BPV) was defined using BPV standard deviation at first 3 days of hospitalization. Post-stroke cognitive impairment was defined as a score of <26 in Montreal Cognitive Assesment-lndonesian Version (MoCA-Ina) assessment. Chi square were used to investigate relation between daytime systolic/diastolic BPV (11.00, 16.00) and nighttime systolic/diastolic (04.00, 23.00) BPV with post-stroke cognitive impairment.

Results : There were 36 patients fulfilling inclusion criteria between March 2014-February 2015, 26 of whom (72.2%) had post-stroke cognitive impairment. No association between age, sex, cigarette smoking, history of stroke/TIA, diabetes mellitus (DM), and hypercholesterolemia with post-stroke cognitive impairment were identified (p > 0.05). All parameters of systolic, 72-hour diastolic and daytime diastolic BPV were not associated with cognitive impairment (p > 0.05). Higher variability in nighttime diastolic blood pressure showed significant association with post-stroke cognitive impairment (OR: 6.4; 95%CI, 1.12-36.43; p = 0.030).

Conclusion : Higher nighttime diastolic BPV was associated with post-stroke cognitive impairment.
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