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Blood Pressure Variability and Cognitive Impairment in Acute Ischemic Stroke Patients (presented at 10th Scientific Meeting of Indonesian Society of Hypertension, Jakarta, 12-14 February 2016)
Bibliografi
Author:
Sani, Tara Puspitarini
;
Andrian, Yonathan
;
Subrata, Irene Halim
;
Suryakusuma, Linda
;
Turana, Yuda
Topik:
Blood pressure variability
;
post-stroke cognitive impairment
;
acute ischemic stroke
;
JABFUNG-FKIK-YDT-2021-71
Bahasa:
(EN )
Penerbit:
Indonesian Society of Hypertension
Tempat Terbit:
Jakarta
Tahun Terbit:
2016
Jenis:
Poster - pada seminar nasional
Fulltext:
B71 Prosiding Poster Nasional.pdf
(2.2MB;
3 download
)
Abstract
Background: Vascular risk factors have significant impact on post-stroke cognitive impairment. Blood pressure variability has emerged as a novel vascular risk factor to affect cognitive functions.
Objective : Defining relation between blood pressure variability (BPV) and cognitive impairment in acute ischemic stroke patients.
Methods : This is a cross-sectional, retrospective study. Inclusion: Stroke patients admitted to Atma Jaya Hospital during first seven days after onset, age >= 18. Exclusion: death endpoint, NIHSS >= 15, aphasia. We evaluated Blood Pressure (BP) of acute ischemic stroke patients 4 times per day. Blood Pressure variability (BPV) was defined using BPV standard deviation at first 3 days of hospitalization. Post-stroke cognitive impairment was defined as a score of <26 in Montreal Cognitive Assesment-lndonesian Version (MoCA-Ina) assessment. Chi square were used to investigate relation between daytime systolic/diastolic BPV (11.00, 16.00) and nighttime systolic/diastolic (04.00, 23.00) BPV with post-stroke cognitive impairment.
Results : There were 36 patients fulfilling inclusion criteria between March 2014-February 2015, 26 of whom (72.2%) had post-stroke cognitive impairment. No association between age, sex, cigarette smoking, history of stroke/TIA, diabetes mellitus (DM), and hypercholesterolemia with post-stroke cognitive impairment were identified (p > 0.05). All parameters of systolic, 72-hour diastolic and daytime diastolic BPV were not associated with cognitive impairment (p > 0.05). Higher variability in nighttime diastolic blood pressure showed significant association with post-stroke cognitive impairment (OR: 6.4; 95%CI, 1.12-36.43; p = 0.030).
Conclusion : Higher nighttime diastolic BPV was associated with post-stroke cognitive impairment.
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