Script Generation as an Indicator of Knowledge Representation in Patients with Alzheimer's Disease.  

Oleh:

Sunderland, Trey ; Martinez, Rick ; Thompson, Karen ; Lawlor, Brian A. ; Weingartner, Herbert ; Grafman, Jordan

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Brain and Language (Full Text) vol. 40 no. 3 (Apr. 1991), page 344-358.

Ketersediaan

Perpustakaan PKBB Nomor Panggil: 405/BAL/40 Non-tandon: tidak ada Tandon: 1

Lihat Detail Induk

Isi artikel

We examined script and lexical retrieval in patients with probable DementiaAlzheimer's Type (DAT), Depressed patients, and normal controls. DAT patient breakdown in script production was structurally similar to their impaired lexical retrieval such that script events of low frequency and low centrality value were lost first. DA T patients also produced more events that fell outside the script boundary as well as more event -order errors. Four cases with DA T were identified on the basis of Z scores whose script production was at least 2 SDs greater than their lexical production or vice versa. This finding suggests that it may be possible to dissociate script and lexical knowledge and production processes. The findings lend partial support for a model of knowledge representation that includes parallel and partially redundant memory networks !hat are distinctly distributed in the brain. @ 1991 Academic Press, Inc.

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