A pituitary adenoma secreting follicle-stimulating hormone with ovarian hyperstimulation: treatment using a gonadotropin-releasing hormone antagonist  

Oleh:

Garmes, Heraldo Mendes ; Grassiotto, Oswaldo Rocha ; Fernandes, Yvens Barbosa ; de Souza Queiroz, Luciano

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 97 no. 01 (Jan. 2012), page 231-234.
Topik: FSH-secreting pituitary tumor; GnRH antagonist; pituitary adenoma; ovarian hyperstimulation syndrome

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2012.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To describe the management of a patient with a pituitary adenoma secreting follicle-stimulating hormone (FSH) associated with ovarian hyperstimulation who was treated with a gonadotropin-releasing hormone (GnRH) antagonist. Design Case report. Setting University teaching hospital. Patient(s) A woman of reproductive age with secondary amenorrhea and ovarian hyperstimulation due to a pituitary adenoma secreting FSH, which persisted after transsphenoidal surgery. Intervention(s) Clinical treatment with a GnRH antagonist. Main Outcome Measure(s) A decrease in serum estradiol levels. Result(s) During the treatment period, ovarian hyperstimulation decreased as shown by a reduction in estradiol levels and an improvement in the patient’s clinical condition and in the ultrasonography parameters. Conclusion(s) The GnRH antagonist was found to be effective for the short-term treatment of ovarian hyperstimulation secondary to a pituitary adenoma secreting FSH, thus representing a therapeutic option that should be taken into consideration in such cases.

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