Keloidal Morphea  

Oleh:

Herridge, Margaret S. ; Tansey, Catherine M. ; Matte, Andrea

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 364 no. 14 (Apr. 2011), page 364:e28.
Topik: Hyperpigmentation
Fulltext: Keloidal Morphea.jpeg (233.46KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2011.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

A 44-year-old woman presented with a 2-year history of multiple enlarging, painful nodules. Physical examination revealed several irregularly shaped, firm nodules with hyperpigmentation and induration on the trunk and upper arms (Panel A). She reported no other concerns about her health, and physical examination showed no other abnormal findings. Neither she nor her family had a history of keloidal scars or systemic sclerosis. The results of laboratory investigations, including assays for antinuclear and anti-dsDNA antibodies and screening for extractable nuclear antigens (including anti-Jo-1, anti-SSA, anti-SSB, anti-Scl-70, anti-Sm, and anti-RNP antibodies) were unremarkable. Findings on examination of a specimen from a skin biopsy were consistent with a diagnosis of keloid formation, except for the presence of perieccrine lymphocytic infiltration. On the basis of these clinical and pathological features, the nodules were diagnosed as keloidal morphea, a rare form of localized cutaneous scleroderma. Despite multiple treatments, the lesions enlarged over a 10-year period (Panel B).

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